An Open-label, Multi-drug, Multi-center Phase II Combination Study of AZD4635 in Patients With Prostate Cancer.
Latest Information Update: 21 Mar 2024
At a glance
- Drugs Durvalumab (Primary) ; Imaradenant (Primary) ; Oleclumab (Primary)
- Indications Prostate cancer
- Focus Therapeutic Use
- Sponsors AstraZeneca
- 02 Mar 2024 Results evaluating the A2AR antagonist AZD4635 in combination with durvalumab or oleclumab in patients with metastatic castration-resistant prostate cancer, published in the Cancer Immunology Immunotherapy
- 29 May 2023 Status changed from active, no longer recruiting to completed.
- 18 Feb 2023 Interim results from Arm B (Arm A to be reported elsewhere) assessing safety and efficacy (n=30; As of August 10, 2021) of AZD4635 in combination with durvalumab (Arm A) or with durvalumab + cabazitaxel (Arm B) in patients with metastatic castrate-resistant prostate cancer, presented at the 2023 Genitourinary Cancers Symposium.