Trial Profile

A Phase I/Ib Dose Escalation Study of Pegylated Liposomal Doxorubicin (PLD) With Peposertib (M3814) in Platinum - Resistant or Ineligible Ovarian and Related Cancers With Planned Expansions in High Grade Serous (HGSOC) and Low Grade Serous Ovarian Cancer (LGSOC)

Status: Active, no longer recruiting

Phase of Trial: Phase I

Latest Information Update: 05 Sep 2025

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At a glance

Drugs Doxorubicin liposomal (Primary) ; Peposertib (Primary)
Indications Adenocarcinoma; Carcinoma; Fallopian tube cancer; Ovarian cancer; Peritoneal cancer; Sarcoma
Focus Adverse reactions

10 Jun 2025 Planned End Date changed from 1 Jun 2025 to 1 Jun 2026.
10 Jun 2025 Planned primary completion date changed from 1 Jun 2025 to 1 Jun 2026.
26 Nov 2024 Status changed from suspended to active, no longer recruiting.

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