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HEALEY ALS Platform Trial

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Trial Profile

HEALEY ALS Platform Trial

Status: Active, no longer recruiting
Phase of Trial: Phase II/III

Latest Information Update: 29 May 2025

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At a glance

Most Recent Events

  • 28 May 2025 According to a Transposon Therapeutics media release, the TPN-101 has been selected for inclusion in the Phase 2/3 HEALEY ALS Platform Trial. Initiation of the TPN-101 regimen in the HEALEY ALS Platform Trial is expected in Q4 2025
  • 06 Jan 2025 According to a Calico media release, more regimens will become available soon, with the goal of adding approximately three regimens per year.
  • 10 Dec 2024 According to a Clene media release, Clene will meet with the FDA in early 2025 to review and finalize its statistical analysis plan for the EAP NfL biomarker analyses.Survival Pharmacometric Modeling: Provide analyses of NfL and related disease-specific biomarkers linked to clinical survival benefit and clinical changes from the Phase 2 trial data

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