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A Phase 1 Open-label Study to Evaluate the Effect of Multiple Doses of Enzalutamide on the Pharmacokinetics of Substrates of P-glycoprotein (Digoxin) and Breast Cancer Resistant Protein (Rosuvastatin) in Male Subjects With Prostate Cancer

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Trial Profile

A Phase 1 Open-label Study to Evaluate the Effect of Multiple Doses of Enzalutamide on the Pharmacokinetics of Substrates of P-glycoprotein (Digoxin) and Breast Cancer Resistant Protein (Rosuvastatin) in Male Subjects With Prostate Cancer

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 08 Dec 2021

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At a glance

  • Drugs Digoxin (Primary) ; Enzalutamide (Primary) ; Rosuvastatin (Primary)
  • Indications Adenocarcinoma; Prostate cancer
  • Focus Pharmacokinetics
  • Sponsors Astellas Pharma Global Development

    • Most Recent Events

    • 14 Jan 2021 Status changed from active, no longer recruiting to completed.
    • 22 Oct 2020 Planned End Date changed from 1 Dec 2020 to 1 Feb 2021.
    • 23 Aug 2020 Planned End Date changed from 1 Nov 2020 to 1 Dec 2020.

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