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Phase I/II Dose Escalation/Dose Expansion Study of Prexasertib in Combination With Irinotecan and Temozolomide in Patients With Relapsed or Refractory Desmoplastic Small Round Cell Tumor and Rhabdomyosarcoma

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Trial Profile

Phase I/II Dose Escalation/Dose Expansion Study of Prexasertib in Combination With Irinotecan and Temozolomide in Patients With Relapsed or Refractory Desmoplastic Small Round Cell Tumor and Rhabdomyosarcoma

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 25 Feb 2025

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At a glance

  • Drugs Irinotecan (Primary) ; Prexasertib (Primary) ; Temozolomide (Primary)
  • Indications Rhabdomyosarcoma; Soft tissue sarcoma
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 20 Feb 2025 Status changed from active, no longer recruiting to completed.
  • 03 Oct 2024 Planned End Date changed from 1 Sep 2024 to 1 Sep 2025.
  • 03 Oct 2024 Planned primary completion date changed from 1 Sep 2024 to 1 Sep 2025.

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