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Treatment Plan of the HER2/HER3 Bispecific Antibody, MCLA-128, for a Patient With Advanced NRG1-Fusion Positive Solid Tumor

Trial Profile

Treatment Plan of the HER2/HER3 Bispecific Antibody, MCLA-128, for a Patient With Advanced NRG1-Fusion Positive Solid Tumor

Status: Completed
Phase of Trial: Clinical Phase Unknown

Latest Information Update: 27 May 2025

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At a glance

  • Drugs Zenocutuzumab (Primary)
  • Indications Adenocarcinoma; Liver metastases; Non-small cell lung cancer; Pancreatic cancer; Pancreatic ductal carcinoma; Solid tumours
  • Focus Expanded access; Therapeutic Use
  • Sponsors Merus

Most Recent Events

  • 20 May 2025 Status changed from recruiting to completed.
  • 24 Oct 2023 Updated analysis demonstrating efficacy of Zenocutuzumab in patients (n=5) with previously treated advanced/metastatic NRG1+ PDAC were presented at the 48th European Society for Medical Oncology Congress
  • 23 Oct 2023 According to a Merus media release, Interim data from this study presented at the European Society for Medical Oncology Congress (ESMO) Asia Congress 2023.

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