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A Phase 3, Randomized, Double-Blind Study of Trilaciclib or Placebo in Patients Receiving First- or Second-Line Gemcitabine and Carboplatin Chemotherapy for Locally Advanced Unresectable or Metastatic Triple-Negative Breast Cancer (PRESERVE 2)

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Trial Profile

A Phase 3, Randomized, Double-Blind Study of Trilaciclib or Placebo in Patients Receiving First- or Second-Line Gemcitabine and Carboplatin Chemotherapy for Locally Advanced Unresectable or Metastatic Triple-Negative Breast Cancer (PRESERVE 2)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 16 Mar 2025

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At a glance

  • Drugs Carboplatin (Primary) ; Gemcitabine (Primary) ; Trilaciclib (Primary)
  • Indications Advanced breast cancer; Male breast cancer; Myelosuppression; Triple negative breast cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms PRESERVE 2
  • Sponsors G1 Therapeutics

    • Most Recent Events

    • 14 Sep 2024 This trial has been completed in Spain, according to European Clinical Trials Database record.
    • 01 Aug 2024 Status changed from active, no longer recruiting to completed.
    • 24 Jun 2024 Results presented in a G1 Therapeutics Media Release.

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