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A 2-tiered, Phase 2, Rule-based, Intra-patient Dose Escalation Study to Investigate Safety and Feasibility of Vactosertib (TEW-7197) in the Treatment of Anemic Patients With Philadelphia Chromosome-negative MPNs (Ph-neg MPNs)

Trial Profile

A 2-tiered, Phase 2, Rule-based, Intra-patient Dose Escalation Study to Investigate Safety and Feasibility of Vactosertib (TEW-7197) in the Treatment of Anemic Patients With Philadelphia Chromosome-negative MPNs (Ph-neg MPNs)

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 14 Nov 2024

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At a glance

  • Drugs Vactosertib (Primary)
  • Indications Anaemia; Essential thrombocythaemia; Myelodysplastic syndromes; Myelofibrosis; Myeloproliferative disorders; Polycythaemia vera
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 11 Nov 2024 According to ClinicalTrials.gov: US National Institutes of Health, endpoints replace by 8 new safety and efficacy endpoints.
  • 11 Nov 2024 Status changed from recruiting to discontinued.
  • 16 Nov 2023 Planned End Date changed from 1 Sep 2024 to 1 Sep 2025.

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