A Phase IIa Study of Dendritic Cell Vaccines Against Her2/Her3 and Pembrolizumab in Patients With Asymptomatic Brain Metastasis From Triple Negative Breast Cancer (TNBC) or HER2+ Breast Cancer (HER2+BC) or Hormone Receptor Positive (HR+) Breast Cancer

Status: Recruiting

Phase of Trial: Phase II

Latest Information Update: 14 Mar 2025

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At a glance

Drugs Pembrolizumab (Primary) ; Dendritic cell vaccines
Indications Advanced breast cancer; Brain metastases; HER2 positive breast cancer; Triple negative breast cancer
Focus Therapeutic Use

Most Recent Events

14 Feb 2024 Planned End Date changed from 15 Apr 2025 to 15 Dec 2026.
14 Feb 2024 Planned primary completion date changed from 15 Apr 2024 to 15 Jun 2025.
06 Jun 2023 Trial design presented at the 59th Annual Meeting of the American Society of Clinical Oncology

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