Trial Profile

Phase I Study of Adoptive Immunotherapy With CD8+ and CD4+ Memory T Cells Transduced to Express an HA-1-Specific T Cell Receptor (TCR) for Children and Adults With Recurrent Acute Leukemia After Allogeneic Hematopoietic Stem Cell Transplantation (HCT)

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 27 Jun 2025

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At a glance

Drugs HA1 T-cell therapy-HighPassBio (Primary) ; Lymphocyte inhibitors
Indications Acute myeloid leukaemia; Blastic plasmacytoid dendritic cell neoplasm; Chronic myeloid leukaemia; Chronic myelomonocytic leukaemia; Juvenile myelomonocytic leukaemia; Leukaemia; Myelodysplastic syndromes; Precursor cell lymphoblastic leukaemia-lymphoma
Focus Adverse reactions; Therapeutic Use

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