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A Phase 2B, Randomized, Double-blind, Multicenter, Placebo-controlled Study to Evaluate the Efficacy of Bentracimab (PB2452) in Reversing Ticagrelor in Subjects Aged 50 to 80 Years Old

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Trial Profile

A Phase 2B, Randomized, Double-blind, Multicenter, Placebo-controlled Study to Evaluate the Efficacy of Bentracimab (PB2452) in Reversing Ticagrelor in Subjects Aged 50 to 80 Years Old

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 10 Apr 2024

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At a glance

  • Drugs Bentracimab (Primary) ; Aspirin; Ticagrelor
  • Indications Haemorrhage
  • Focus Registrational; Therapeutic Use
  • Sponsors PhaseBio Pharmaceuticals; SFJ Pharmaceuticals

    • Most Recent Events

    • 04 Apr 2022 According to a PhaseBio Pharmaceuticals media release, the Company is commencing preparation of a BLA and targeting submission to the FDA in mid-2022.
    • 04 Apr 2022 According to a PhaseBio Pharmaceuticals media release, the positive data from this Phase 2b trial of bentracimab build on the prior results that have already been published in the New England Journal of Medicine and NEJM Evidence.
    • 04 Apr 2022 According to a PhaseBio Pharmaceuticals media release, results from its Phase 2b clinical trial of bentracimab that were presented on April 2nd during a Late Breaking Featured Clinical Research Presentation at the American College of Cardiologys 71st Annual Scientific Session.

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