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A Phase 1, Open-Label, Randomized, Two-Way Crossover Study to Evaluate the Effect of Single-Dose Intravenous Rifampin as a Prototypic Inhibitor of OATP1B1 and OATP1B3 on the Single-Dose Pharmacokinetics of Oral TAK-906 in Healthy Adult Subjects

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Trial Profile

A Phase 1, Open-Label, Randomized, Two-Way Crossover Study to Evaluate the Effect of Single-Dose Intravenous Rifampin as a Prototypic Inhibitor of OATP1B1 and OATP1B3 on the Single-Dose Pharmacokinetics of Oral TAK-906 in Healthy Adult Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 02 Nov 2021

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At a glance

  • Drugs Trazpiroben (Primary) ; Rifampicin
  • Indications Gastroparesis
  • Focus Pharmacokinetics
  • Sponsors Takeda Oncology

    • Most Recent Events

    • 17 Sep 2021 Results reporting plasma PK parameters of trazpiroben and rifampicin when trazpiroben is administered alone or after an intravenous infusion of rifampin presented at the 2021 American College of Clinical Pharmacology Annual Meeting
    • 04 Dec 2019 Status changed from recruiting to completed.
    • 06 Nov 2019 Status changed from not yet recruiting to recruiting.

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