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Phase I/IIa, Non-Randomised, Open-Label Dose Escalation and Expansion Trial With Isunakinra Alone and in Combination With a PD-1/PD-L1 Inhibitor in Patients With Metastatic or Unresectable, Locally Advanced Malignant Solid Tumors

Trial Profile

Phase I/IIa, Non-Randomised, Open-Label Dose Escalation and Expansion Trial With Isunakinra Alone and in Combination With a PD-1/PD-L1 Inhibitor in Patients With Metastatic or Unresectable, Locally Advanced Malignant Solid Tumors

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 08 Aug 2024

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At a glance

  • Drugs Isunakinra (Primary)
  • Indications Anal cancer; Appendiceal cancer; Cholangiocarcinoma; Colorectal cancer; Pancreatic cancer; Prostate cancer; Solid tumours; Triple negative breast cancer
  • Focus Adverse reactions
  • Sponsors Buzzard Pharmaceuticals

Most Recent Events

  • 06 Aug 2024 Status changed from recruiting to completed.
  • 06 Jun 2023 Results (n=15), presented at the 59th Annual Meeting of the American Society of Clinical Oncology
  • 20 Feb 2023 Planned End Date changed from 15 Jul 2023 to 15 Dec 2024.

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