A Prospective, Open-label, Multicenter Phase-II Trial to Evaluate the Efficacy and Safety of Zanubrutinib (BGB-3111), a BTK Inhibitor, Plus Tislelizumab (BGB-A317), a PD1 Inhibitor, for Treatment of Patients With Richter Transformation With or Without SonrotoclaxBGB-11417), a Bcl-2 Inhibitor (CLL-RT1-trial of the GCLLSG)
Latest Information Update: 06 Jan 2025
At a glance
- Drugs Tislelizumab (Primary) ; Zanubrutinib (Primary)
- Indications Richter's syndrome
- Focus Therapeutic Use
- Acronyms CLL-RT1
Most Recent Events
- 15 Jul 2024 Planned number of patients changed from 57 to 83.
- 15 Jul 2024 Status changed from active, no longer recruiting to recruiting.
- 15 Jul 2024 Planned End Date changed from 1 Dec 2024 to 1 Aug 2026.