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A Randomized Phase 3 Multicenter Open-Label Study to Compare the Efficacy of TAK-788 as First-Line Treatment Versus Platinum-Based Chemotherapy in Patients With Non-Small Cell Lung Cancer With EGFR Exon 20 Insertion Mutations

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Trial Profile

A Randomized Phase 3 Multicenter Open-Label Study to Compare the Efficacy of TAK-788 as First-Line Treatment Versus Platinum-Based Chemotherapy in Patients With Non-Small Cell Lung Cancer With EGFR Exon 20 Insertion Mutations

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 28 Apr 2025

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At a glance

  • Drugs Mobocertinib (Primary) ; Carboplatin; Cisplatin; Pemetrexed
  • Indications Non-small cell lung cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms EXCLAIM 2
  • Sponsors Takeda Oncology

Most Recent Events

  • 22 Apr 2025 Planned End Date changed from 30 Sep 2026 to 31 Oct 2026.
  • 22 Apr 2025 Planned primary completion date changed from 30 Sep 2026 to 31 Oct 2026.
  • 17 Mar 2025 Planned End Date changed from 31 Jul 2025 to 30 Sep 2026.

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