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Phase 2, Open-Label, Dose-Escalation and Dose-Expansion Study of Infigratinib, an FGFR 1-3-Selective Tyrosine Kinase Inhibitor, in Children with Achondroplasia: PROPEL 2

Trial Profile

Phase 2, Open-Label, Dose-Escalation and Dose-Expansion Study of Infigratinib, an FGFR 1-3-Selective Tyrosine Kinase Inhibitor, in Children with Achondroplasia: PROPEL 2

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 02 Apr 2025

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At a glance

  • Drugs Infigratinib (Primary)
  • Indications Achondroplasia
  • Focus Adverse reactions; Pharmacokinetics; Proof of concept; Therapeutic Use
  • Acronyms PROPEL2
  • Sponsors QED Therapeutics
  • Most Recent Events

    • 26 Mar 2025 Status changed from active, no longer recruiting to completed.
    • 18 Nov 2024 Results presented in the BridgeBio Media Release.
    • 18 Nov 2024 According to BridgeBio media release, Primary endpoint (Change from baseline in annualized height velocity) has been met.

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