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A Phase 2, Multicohort Open-Label Study of JNJ-68284528, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against BCMA in Subjects With Multiple Myeloma

Trial Profile

A Phase 2, Multicohort Open-Label Study of JNJ-68284528, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against BCMA in Subjects With Multiple Myeloma

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 09 Apr 2025

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At a glance

  • Drugs Ciltacabtagene autoleucel (Primary) ; Bortezomib; Cyclophosphamide; Daratumumab; Dexamethasone; Dexamethasone; Fludarabine; Lenalidomide
  • Indications Multiple myeloma
  • Focus Therapeutic Use
  • Acronyms CARTITUDE-2
  • Sponsors Janssen Research & Development; Janssen-Cilag

Most Recent Events

  • 17 Jul 2024 Planned number of patients changed from 157 to 237.
  • 17 Jul 2024 Status changed from active, no longer recruiting to recruiting.
  • 18 Jun 2024 Planned primary completion date changed from 30 May 2025 to 1 Dec 2025.

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