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A Phase 2 Study of ALKS 4230 in Combination With Anti-PD-1 (Pembrolizumab) in Patients With Advanced or Recurrent Head and Neck Squamous Cell Cancer Currently on Treatment With Anti-PD-(L)1 Without Having Achieved a Complete Remission

Trial Profile

A Phase 2 Study of ALKS 4230 in Combination With Anti-PD-1 (Pembrolizumab) in Patients With Advanced or Recurrent Head and Neck Squamous Cell Cancer Currently on Treatment With Anti-PD-(L)1 Without Having Achieved a Complete Remission

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 21 Oct 2024

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At a glance

  • Drugs Nemvaleukin-alfa (Primary) ; Pembrolizumab (Primary)
  • Indications Head and neck cancer; Squamous cell cancer
  • Focus Therapeutic Use
  • Acronyms ION-01
  • Sponsors Alkermes plc; Mural Oncology
  • Most Recent Events

    • 10 Nov 2022 Status changed from active, no longer recruiting to completed.
    • 16 Feb 2022 According to an Alkermes plc media release, data from the study was presented at the Society for Immunotherapy of Cancer's (SITC) 36th Annual Meeting.
    • 03 Nov 2021 According to an Alkermes media release, data will be presented at the Society for Immunotherapy of Cancer's (SITC) 36th Annual Meeting.

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