A Phase 1 / 2 Study to Evaluate the Safety, Tolerability and Initial Anti-Tumor Activity of Adoptively Transferred T Lymphocytes Targeting WT1, PRAME and Cyclin A1 AML or MDS Patients With Relapsed Disease After Matched Allogeneic HCT
Latest Information Update: 18 Jan 2024
At a glance
- Drugs NEXI 001 (Primary) ; Cyclophosphamide; Fludarabine
- Indications Acute myeloid leukaemia; Myelodysplastic syndromes
- Focus Adverse reactions; First in man; Proof of concept; Therapeutic Use
- Sponsors NexImmune
Most Recent Events
- 12 Jan 2024 Planned End Date changed from 1 Mar 2023 to 1 Mar 2025.
- 12 Jan 2024 Planned primary completion date changed from 1 Oct 2022 to 1 Oct 2024.
- 12 Jan 2024 Status changed from recruiting to active, no longer recruiting.