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A Phase 1, Open-Label, Single Ascending Dose Study to Assess the Safety and Tolerability of a Single Intravitreal Injection of UBX1325 in Patients With Diabetic Macular Edema or Neovascular Age-Related Macular Degeneration

Trial Profile

A Phase 1, Open-Label, Single Ascending Dose Study to Assess the Safety and Tolerability of a Single Intravitreal Injection of UBX1325 in Patients With Diabetic Macular Edema or Neovascular Age-Related Macular Degeneration

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 17 Apr 2024

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At a glance

  • Drugs Foselutoclax (Primary)
  • Indications Diabetic macular oedema
  • Focus Adverse reactions; First in man
  • Sponsors UNITY Biotechnology

Most Recent Events

  • 15 Apr 2024 According to a UNITY BIOTECHNOLOGY media release, the Company published new research in Nature Medicine, "Therapeutics targeting of cellular senescence in diabetic macular edema: preclinical and phase 1 trial results.
  • 08 Mar 2022 Status changed from active, no longer recruiting to completed.
  • 04 Jan 2022 According to an UNITY Biotechnology media release, complete safety and efficacy data through 24 weeks from the additional wet AMD cohort is expected in 1H 2022.

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