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Feasibility and Safety of Neoadjuvant Nivolumab and Chemotherapy for Resectable Malignant Pleural Mesothelioma

Trial Profile

Feasibility and Safety of Neoadjuvant Nivolumab and Chemotherapy for Resectable Malignant Pleural Mesothelioma

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 30 Jun 2025

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At a glance

  • Drugs Carboplatin (Primary) ; Cisplatin (Primary) ; Nivolumab (Primary) ; Pemetrexed (Primary)
  • Indications Malignant-mesothelioma
  • Focus Adverse reactions

Most Recent Events

  • 25 Jun 2025 Planned End Date changed from 1 Nov 2025 to 1 Nov 2026.
  • 25 Jun 2025 Planned primary completion date changed from 1 Nov 2025 to 1 Nov 2026.
  • 30 Apr 2025 Results assessing the feasibility and clinical outcomes of neoadjuvant nivolumab combined with platinum (cisplatin/carboplatin) and pemetrexed in patients with respectable diffuse pleural mesothelioma were published at the 116th Annual Meeting of the American Association for Cancer Research.

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