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A Randomized, Double-Blind, Placebo-Controlled Multicenter Phase III Trial of Alpha 1 - Antitrypsin (AAT) Combined With Corticosteroids vs Corticosteroids Alone for the Treatment of High Risk Acute Graft-versus-Host Disease (GVHD) Following Allogeneic Hematopoietic Stem Cell Transplant (BMT CTN 1705)

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Trial Profile

A Randomized, Double-Blind, Placebo-Controlled Multicenter Phase III Trial of Alpha 1 - Antitrypsin (AAT) Combined With Corticosteroids vs Corticosteroids Alone for the Treatment of High Risk Acute Graft-versus-Host Disease (GVHD) Following Allogeneic Hematopoietic Stem Cell Transplant (BMT CTN 1705)

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 13 Feb 2025

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At a glance

  • Drugs Alpha 1-antitrypsin (Primary) ; Corticosteroids
  • Indications Graft-versus-host disease
  • Focus Registrational; Therapeutic Use
  • Sponsors CSL Behring

Most Recent Events

  • 10 Feb 2025 Planned End Date changed from 12 Dec 2024 to 12 May 2025.
  • 30 Jul 2024 Planned End Date changed from 1 May 2024 to 12 Dec 2024.
  • 05 Feb 2024 Status changed from recruiting to active, no longer recruiting.

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