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Open-Label Safety Study of Glial Cell Line-Derived Neurotrophic Factor Gene Transfer (AAV2- GDNF) in Parkinson's Disease

Trial Profile

Open-Label Safety Study of Glial Cell Line-Derived Neurotrophic Factor Gene Transfer (AAV2- GDNF) in Parkinson's Disease

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 30 May 2025

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At a glance

  • Drugs AB 1005 (Primary)
  • Indications Parkinson's disease
  • Focus Adverse reactions
  • Sponsors Brain Neurotherapy Bio

Most Recent Events

  • 27 May 2025 According to AskBio Media Release, company announced today the recent publication of the complete results of its Phase 1b trial of AB-1005, a glial cell line-derived neurotrophic factor (GDNF) investigational gene therapy for the treatment of Parkinson's disease (PD), in Movement Disorders, an official peer reviewed journal of the International Parkinson and Movement Disorder Society.
  • 27 May 2025 Results presented in the AskBio Media Release.
  • 14 Jan 2025 According to a Bayer media release, 36-month Phase Ib data presented at the International Congress of Parkinson's Disease and Movement Disorders, which was held in Philadelphia, Pennsylvania, from September 27 to October 1, 2024.

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