Trial Profile

Phase I/IIa, First-in-human, Open-label, Dose Escalation Trial With Expansion Cohorts to Evaluate Safety and Preliminary Efficacy of CLDN6 CAR-T With or Without CLDN6 RNA-LPX in Patients With CLDN6-positive Relapsed or Refractory Advanced Solid Tumors

Status: Active, no longer recruiting

Phase of Trial: Phase I

Latest Information Update: 23 Jun 2026

Price :

$35 ^*

Note:

Adis is an information provider.
Final gross price and currency may vary according to local VAT and billing address.
Your purchase entitles you to full access to the information contained in our trial profile at the time of purchase.
A link to download a PDF version of the trial profile will be included in your email receipt.

At a glance

Drugs BNT 211 (Primary)
Indications Carcinoma; Endometrial cancer; Fallopian tube cancer; Gastric cancer; Germ cell cancer; Non-small cell lung cancer; Ovarian cancer; Peritoneal cancer; Sarcoma; Solid tumours; Squamous cell cancer; Testicular cancer; Uterine cancer
Focus Adverse reactions; First in man
Sponsors BioNTech

18 Jun 2026 Status changed from recruiting to active, no longer recruiting.
17 Apr 2026 Planned End Date changed from 1 Jan 2041 to 1 Aug 2041.
17 Apr 2026 Planned primary completion date changed from 1 Dec 2028 to 1 Aug 2028.

If your organization or you do not have a subscription, try one of the following:

Contacting your organization’s admin about adding this content to your AdisInsight subscription
Buying a PDF version of any individual profile
Request a free trial (opens in a new window)

If your organization has a subscription, there are several access options, even while working remotely:

Working within your organization’s network
Login with username/password or try to access via your institution
Persisted access using your organization’s identifier stored in your user browser for 90 days

For assistance, contact us at asktheexpert.adisinsight@springer.com