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An Open-label, Multi-center, Phase 1b/2a Basket Trial of IDX-1197 in Patients with Homologous Recombination Repair Mutated Solid Tumors

Trial Profile

An Open-label, Multi-center, Phase 1b/2a Basket Trial of IDX-1197 in Patients with Homologous Recombination Repair Mutated Solid Tumors

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 01 Oct 2024

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At a glance

  • Drugs Venadaparib (Primary)
  • Indications Biliary cancer; Breast cancer; Carcinoma; Gastric cancer; Ovarian cancer; Pancreatic cancer; Small cell lung cancer; Solid tumours; Urogenital cancer
  • Focus Therapeutic Use
  • Acronyms VASTUS
  • Sponsors Idience; Ildong Pharmaceutical
  • Most Recent Events

    • 27 Sep 2024 Status changed from active, no longer recruiting to completed.
    • 06 Jun 2023 Results of an exploratory analysis to explore genetic alterations co-existing with HRR mutation to better predict efficacy from a monotherapy of venadaparib in patients with metastatic pancreatic cancer presented at the 59th Annual Meeting of the American Society of Clinical Oncology
    • 28 Feb 2023 Planned End Date changed from 31 Dec 2024 to 31 Dec 2023.

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