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A Multicenter, Open-label,Phase 1b/2 Study for Safety and Efficacy of AK104, a PD-1/CTLA-4 Bispecific Antibody, in Selected Advanced Solid Tumors

Trial Profile

A Multicenter, Open-label,Phase 1b/2 Study for Safety and Efficacy of AK104, a PD-1/CTLA-4 Bispecific Antibody, in Selected Advanced Solid Tumors

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 24 Oct 2023

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At a glance

  • Drugs Cadonilimab (Primary)
  • Indications Malignant melanoma; Non-small cell lung cancer; Solid tumours
  • Focus Therapeutic Use
  • Sponsors Akeso Biopharma

Most Recent Events

  • 01 Oct 2023 Primary endpoint (Anti-tumor activity of AK104 using objective response rate (ORR) based on RECIST v1.1 as assessed by the investigator for NSCLC cohort) has not been met according to result published in the Lung Cancer.
  • 01 Oct 2023 Results assessing (n=53) efficacy and safety of cadonilimab (anti PD-1 and CTLA-4 bispecific antibody) in patients with previously treated metastatic non-small-cell lung cancer published in the Lung Cancer
  • 08 Oct 2022 Status changed from not yet recruiting to completed.

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