Trial Profile

An Open-label, Multi-center, Long-term Extension Study of Zanubrutinib (BGB-3111) Regimens in Patients With B-cell Malignancies

Status: Active, no longer recruiting

Phase of Trial: Phase III

Latest Information Update: 24 Oct 2025

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At a glance

Drugs Tislelizumab (Primary) ; Zanubrutinib (Primary)
Indications B-cell leukaemia; B-cell lymphoma
Focus Adverse reactions; Registrational
Acronyms BGB-3111-LTE1
Sponsors BeOne Medicines

Most Recent Events

21 Oct 2025 Planned End Date changed from 1 Jun 2027 to 1 Dec 2028.
21 Oct 2025 Planned primary completion date changed from 1 Dec 2026 to 1 Nov 2027.
03 Oct 2025 Planned End Date changed from 1 Dec 2028 to 1 Jun 2027.

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