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A Phase I Open-label, Dose Escalation Study to Investigate the Safety, Tolerability, Pharmacokinetics, Immunogenicity and Clinical Activity of the Antibody Drug Conjugate GSK2857916 in Chinese Participants With Relapsed/Refractory Multiple Myeloma Who Have Failed At Least Two Lines of Previous Treatment, Containing an Alkylator, a Proteasome Inhibitor and an Immunomodulatory Agent

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Trial Profile

A Phase I Open-label, Dose Escalation Study to Investigate the Safety, Tolerability, Pharmacokinetics, Immunogenicity and Clinical Activity of the Antibody Drug Conjugate GSK2857916 in Chinese Participants With Relapsed/Refractory Multiple Myeloma Who Have Failed At Least Two Lines of Previous Treatment, Containing an Alkylator, a Proteasome Inhibitor and an Immunomodulatory Agent

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 24 Mar 2025

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At a glance

  • Drugs Belantamab mafodotin (Primary)
  • Indications Multiple myeloma
  • Focus Adverse reactions
  • Sponsors GlaxoSmithKline; GSK

Most Recent Events

  • 08 Feb 2022 Status changed from active, no longer recruiting to completed.
  • 12 Oct 2021 Planned number of patients changed from 12 to 6.
  • 12 Oct 2021 Planned End Date changed from 31 Jul 2021 to 31 Aug 2022.

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