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Randomized Phase III Study of Combination Osimertinib (AZD9291) and Bevacizumab Versus Osimertinib (AZD9291) Alone as First-Line Treatment for Patients With Metastatic EGFR-Mutant Non-Small Cell Lung Cancer (NSCLC)

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Trial Profile

Randomized Phase III Study of Combination Osimertinib (AZD9291) and Bevacizumab Versus Osimertinib (AZD9291) Alone as First-Line Treatment for Patients With Metastatic EGFR-Mutant Non-Small Cell Lung Cancer (NSCLC)

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 05 Jul 2025

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At a glance

  • Drugs Bevacizumab (Primary) ; Osimertinib (Primary)
  • Indications Non-small cell lung cancer
  • Focus Therapeutic Use

Most Recent Events

  • 18 Mar 2023 Planned End Date changed from 1 Sep 2025 to 31 Dec 2026.
  • 18 Mar 2023 Planned primary completion date changed from 1 Sep 2025 to 31 Dec 2026.
  • 04 Nov 2020 Status changed from not yet recruiting to recruiting.

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