First Line Treatment With VeNEtoclaX and ibruTinib Induction Followed by Obinutuzumab intenSificaTion Exclusively in CLL/SLL Patients Not in Complete Remission and/or With Detectable Bone Marrow Minimal Residual Disease (NEXT STEP Trial)
Latest Information Update: 10 Feb 2025
At a glance
- Drugs Ibrutinib (Primary) ; Obinutuzumab (Primary) ; Venetoclax (Primary)
- Indications Chronic lymphocytic leukaemia
- Focus Therapeutic Use
- Acronyms HOVON 158; NEXT STEP trial
Most Recent Events
- 13 Dec 2022 Interim results (n=30) evaluating safety and efficacy of patients until the end of cycle 8, presented at the 64th American Society of Hematology Annual Meeting and Exposition.
- 20 Aug 2021 Status changed from recruiting to active, no longer recruiting.
- 05 Dec 2019 New trial record