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A Phase 4, Randomized, Multicenter, Open-Label, 2-Dosage Regimen, Safety and Tolerability, Efficacy, Pharmacokinetic, and Pharmacodynamic Study of Asfotase Alfa in Adult Patients With Pediatric-Onset Hypophosphatasia

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Trial Profile

A Phase 4, Randomized, Multicenter, Open-Label, 2-Dosage Regimen, Safety and Tolerability, Efficacy, Pharmacokinetic, and Pharmacodynamic Study of Asfotase Alfa in Adult Patients With Pediatric-Onset Hypophosphatasia

Status: Withdrawn prior to enrolment
Phase of Trial: Phase IV

Latest Information Update: 03 Nov 2023

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At a glance

  • Drugs Asfotase alfa (Primary)
  • Indications Hypophosphatasia
  • Focus Pharmacokinetics
  • Acronyms REBUILD
  • Sponsors Alexion AstraZeneca Rare Disease

Most Recent Events

  • 03 Jun 2020 Status changed from not yet recruiting to withdrawn prior to enrolment.
  • 23 Jan 2020 Planned initiation date changed from 1 Dec 2019 to 1 Apr 2020.
  • 09 Dec 2019 New trial record

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