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A Phase 1, Open-Label, Dose-Escalation and Expansion Study of IK-175, an Oral Aryl Hydrocarbon Receptor (AHR) Inhibitor in Patients With Locally Advanced or Metastatic Solid Tumors and Urothelial Carcinoma

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Trial Profile

A Phase 1, Open-Label, Dose-Escalation and Expansion Study of IK-175, an Oral Aryl Hydrocarbon Receptor (AHR) Inhibitor in Patients With Locally Advanced or Metastatic Solid Tumors and Urothelial Carcinoma

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 02 Jul 2024

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At a glance

  • Drugs IK 175 (Primary) ; Nivolumab (Primary) ; Checkpoint kinase inhibitors
  • Indications Carcinoma; Solid tumours; Urogenital cancer
  • Focus Adverse reactions; First in man
  • Sponsors Ikena Oncology

Most Recent Events

  • 04 Jun 2024 Results presented at the 60th Annual Meeting of the American Society of Clinical Oncology
  • 14 Mar 2024 Status changed from active, no longer recruiting to completed.
  • 10 Aug 2023 According to an Ikena Oncology media release, this trial has completed enrollment and the program is eligible for opt-in from Bristol Myers Squibb through early 2024.

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