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Evaluation on the Tolerance and Preliminary Efficacy of Sintilimab (IBI308) Combined With Bevacizumab, Oxaliplatin and Capecitabine Regimen for Ras Gene Mutant and Microsatellite Stable Unresectable Metastatic Colorectal Cancer

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Trial Profile

Evaluation on the Tolerance and Preliminary Efficacy of Sintilimab (IBI308) Combined With Bevacizumab, Oxaliplatin and Capecitabine Regimen for Ras Gene Mutant and Microsatellite Stable Unresectable Metastatic Colorectal Cancer

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 03 Jul 2024

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At a glance

  • Drugs Bevacizumab (Primary) ; Capecitabine (Primary) ; Oxaliplatin (Primary) ; Sintilimab (Primary)
  • Indications Adenocarcinoma; Colorectal cancer
  • Focus Adverse reactions; Therapeutic Use

    • Most Recent Events

    • 04 Jun 2024 Updated survival results , presented at the 60th Annual Meeting of the American Society of Clinical Oncology
    • 09 Mar 2023 According to ClinicalTrials.gov record, protocol has been amended to decrease the patient number from 436 to 25, Phase was also changed from Phase III to Phase II. Trial focus was also changed from TU to AR and TU.
    • 09 Mar 2023 Planned number of patients changed from 436 to 25.

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