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A Phase I, First-In-Human, Multicenter, Open-Label Dose Escalation and Dose Expansion Study of ABM-1310, as a Monotherapy and a Combination Therapy, Administered Orally in Adult Patients With Advanced Solid Tumors Harboring BRAF Mutations

Trial Profile

A Phase I, First-In-Human, Multicenter, Open-Label Dose Escalation and Dose Expansion Study of ABM-1310, as a Monotherapy and a Combination Therapy, Administered Orally in Adult Patients With Advanced Solid Tumors Harboring BRAF Mutations

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 01 Jul 2024

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At a glance

  • Drugs ABM 1310 (Primary) ; Cobimetinib (Primary)
  • Indications CNS cancer; Glioblastoma; Glioma; Malignant melanoma; Solid tumours
  • Focus Adverse reactions; First in man
  • Sponsors ABM Therapeutics

Most Recent Events

  • 04 Jun 2024 Interim Results (Results: As of 28 Nov 2023, n=51 ) presented at the 60th Annual Meeting of the American Society of Clinical Oncology
  • 17 May 2024 Status changed from active, no longer recruiting to discontinued.
  • 30 Jan 2024 Status changed from recruiting to active, no longer recruiting.

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