A 28 days phase 2a proof of concept study assessing the ability of AT-001, a novel inhibitor of aldose reductase, to normalize the intracellular utilization of glucose by inhibiting its aberrant metabolism to sorbitol, and to reduce NTproBNP levels
Latest Information Update: 14 Dec 2019
At a glance
- Drugs Caficrestat (Primary)
- Indications Diabetic cardiomyopathy; Type 2 diabetes mellitus
- Focus Pharmacodynamics; Proof of concept
- 14 Dec 2019 New trial record
- 18 Nov 2019 Results presented at the American Heart Association Scientific Sessions 2019