Trial Profile

A study to assess drug interactions of Direct Oral Anticoagulants with multiple prescription medications and their impact on outcomes in patients with atrial fibrillation

Status: Completed

Phase of Trial: Phase IV

Latest Information Update: 18 Nov 2021

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At a glance

Drugs Apixaban (Primary) ; Dabigatran etexilate (Primary) ; Rivaroxaban (Primary) ; Amiodarone; Carbamazepine; Ciclosporin; Citalopram; Clarithromycin; Desvenlafaxine; Diltiazem; Dronedarone; Duloxetine; Erythromycin; Escitalopram; Fluconazole; Fluoxetine; Fluvoxamine; Itraconazole; Ketoconazole; Levomilnacipran; Milnacipran; Paroxetine; Phenytoin; Quinidine; Rifampicin; Venlafaxine; Verapamil
Indications Stroke; Thromboembolism; Transient ischaemic attacks
Focus Adverse reactions; Therapeutic Use

27 Oct 2021 Results published in the American Journal of Cardiology
14 Dec 2019 New trial record
18 Nov 2019 Results presented at the American Heart Association Scientific Sessions 2019.

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