Trial Profile

Randomized Phase 2 Trial of CPX-351 (Vyxeos) vs. CLAG-M (Cladribine, Cytarabine, G-CSF, and Mitoxantrone) in Medically Less-Fit Adults With Acute Myeloid Leukemia (AML) or Other High-Grade Myeloid Neoplasm

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 26 Mar 2025

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At a glance

Drugs Cladribine (Primary) ; Cytarabine (Primary) ; Cytarabine/daunorubicin (Primary) ; Granulocyte colony-stimulating factors (Primary) ; Mitoxantrone (Primary)
Indications Acute myeloid leukaemia
Focus Therapeutic Use

24 Mar 2025 Planned primary completion date changed from 31 May 2025 to 30 Jun 2025.
24 Mar 2025 Status changed from recruiting to active, no longer recruiting.
22 Mar 2023 Planned End Date changed from 31 Dec 2026 to 31 Dec 2027.

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