Trial Profile

An Open-Label, Multicenter, First-in-Human, Dose-Escalation, Multicohort, Phase 1/2 Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab in Subjects With Locally Advanced or Metastatic Solid Tumors

Status: Active, no longer recruiting

Phase of Trial: Phase I/II

Latest Information Update: 22 Dec 2025

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At a glance

Drugs INBRX 106 (Primary) ; Pembrolizumab (Primary)
Indications Adenocarcinoma; Gastric cancer; Head and neck cancer; Malignant melanoma; Nasopharyngeal cancer; Non-small cell lung cancer; Oesophageal cancer; Renal cell carcinoma; Solid tumours; Squamous cell cancer; Urogenital cancer; Uveal melanoma
Focus Adverse reactions; First in man; Therapeutic Use
Sponsors Inhibrx

18 Dec 2025 Status changed from recruiting to active, no longer recruiting.
16 Sep 2025 Planned End Date changed from 15 May 2026 to 12 May 2027.
16 Sep 2025 Planned primary completion date changed from 2 Feb 2026 to 30 Oct 2026.

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