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A multi-centre, open-label, phase 1 study, Part A single ascending dose and Part B multiple dose, to evaluate the safety, tolerability and pharmacokinetics, and to explore early signs of effectiveness of induction of antigen-specific immune tolerance with TPM203 in pemphigus vulgaris patients

Trial Profile

A multi-centre, open-label, phase 1 study, Part A single ascending dose and Part B multiple dose, to evaluate the safety, tolerability and pharmacokinetics, and to explore early signs of effectiveness of induction of antigen-specific immune tolerance with TPM203 in pemphigus vulgaris patients

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 11 Sep 2023

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At a glance

  • Drugs TPM 203 (Primary)
  • Indications Pemphigus vulgaris
  • Focus Adverse reactions; First in man
  • Sponsors Topas Therapeutics

Most Recent Events

  • 30 Aug 2023 Status changed from recruiting to completed.
  • 23 Dec 2019 New trial record
  • 18 Dec 2019 According to a Topas Therapeutics media release, first patient has been enrolled. The coordinating investigator is Prof. Michael Hertl from the Dept. of Dermatology and Allergology at University Medical Center Marburg.

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