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An Open-Label Feasibility Study to Assess the Safety and Pharmacokinetics of Enasidenib in Pediatric Patients With Relapsed/Refractory Acute Myeloid Leukemia (R/R-AML) With an Isocitrate Dehydrogenase-2 (IDH2) Mutation

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An Open-Label Feasibility Study to Assess the Safety and Pharmacokinetics of Enasidenib in Pediatric Patients With Relapsed/Refractory Acute Myeloid Leukemia (R/R-AML) With an Isocitrate Dehydrogenase-2 (IDH2) Mutation

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 21 Mar 2025

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At a glance

  • Drugs Enasidenib (Primary)
  • Indications Acute myeloid leukaemia
  • Focus Adverse reactions; Pharmacokinetics

    • Most Recent Events

    • 26 Oct 2023 Planned initiation date changed from 27 Oct 2023 to 25 Jan 2024.
    • 01 Aug 2023 Treatments section is updated to add these procedures- Biospecimen Collection, Bone Marrow Aspiration and Bone Marrow Biopsy. Upper age limit of inclusion criteria is increased from 18 to 21 years.
    • 14 Feb 2023 Status changed from active, no longer recruiting to recruiting.

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