Trial Profile

A Phase I/II Safety Lead in Study of Ex-Vivo Expanded Allogeneic Universal Donor TGFβi NK Cell Infusions in Combination With Irinotecan, Temozolomide, and Dinutuximab in Patients With Relapsed or Refractory Neuroblastoma: The Allo - STING Trial

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 21 May 2025

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At a glance

Drugs Dinutuximab (Primary) ; Irinotecan (Primary) ; Natural killer cell therapy (Primary) ; Sargramostim (Primary) ; Temozolomide (Primary) ; Temozolomide (Primary)
Indications Neuroblastoma
Focus Adverse reactions; Therapeutic Use
Acronyms STING

13 May 2025 Planned End Date changed from 1 Dec 2025 to 1 Dec 2027.
13 May 2025 Planned primary completion date changed from 1 Dec 2024 to 1 Dec 2026.
04 Jun 2024 Results (n=4) presented at the 60th Annual Meeting of the American Society of Clinical Oncology.

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