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An Open-Label Efficacy and Safety Study of Pozelimab in Patients With CD55-Deficient Protein-Losing Enteropathy (CHAPLE Disease)

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Trial Profile

An Open-Label Efficacy and Safety Study of Pozelimab in Patients With CD55-Deficient Protein-Losing Enteropathy (CHAPLE Disease)

Status: Completed
Phase of Trial: Phase II/III

Latest Information Update: 21 Feb 2025

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At a glance

  • Drugs Pozelimab (Primary) ; Pozelimab (Primary)
  • Indications Protein-losing enteropathy
  • Focus First in man; Registrational; Therapeutic Use
  • Sponsors Regeneron Pharmaceuticals
  • Most Recent Events

    • 08 May 2024 Status changed from active, no longer recruiting to completed.
    • 05 Feb 2024 Results of Evaluating the efficacy and safety of pozelimab published in the Lancet
    • 18 Aug 2023 "According to Regeneron media release, Michael Lenardo is an investigator of the trial."

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