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A Phase I Clinical Trial of Selinexor (KPT-330) in Combination With Temozolomide and Radiation Therapy in Patients With Newly Diagnosed Glioblastoma

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Trial Profile

A Phase I Clinical Trial of Selinexor (KPT-330) in Combination With Temozolomide and Radiation Therapy in Patients With Newly Diagnosed Glioblastoma

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 05 Jun 2025

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At a glance

  • Drugs Selinexor (Primary) ; Temozolomide (Primary) ; Loperamide; Sodium chloride
  • Indications Astrocytoma; Glioblastoma; Gliosarcoma
  • Focus Adverse reactions

Most Recent Events

  • 08 May 2024 Status changed from recruiting to active, no longer recruiting.
  • 20 Jul 2023 Planned primary completion date changed from 30 Aug 2024 to 30 Aug 2025.
  • 16 Oct 2021 Planned End Date changed from 30 Jul 2024 to 30 Jul 2026.

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