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A Phase-2, Two-Cohort Trial of Neoadjuvant Nab-Paclitaxel and Alpelisib in Anthracycline Refractory Triple Negative Breast Cancer With PIK3CA or PTEN Alterations

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Trial Profile

A Phase-2, Two-Cohort Trial of Neoadjuvant Nab-Paclitaxel and Alpelisib in Anthracycline Refractory Triple Negative Breast Cancer With PIK3CA or PTEN Alterations

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 30 Oct 2024

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At a glance

  • Drugs Alpelisib (Primary) ; Paclitaxel (Primary)
  • Indications Advanced breast cancer; Early breast cancer; Triple negative breast cancer
  • Focus Therapeutic Use

Most Recent Events

  • 28 Sep 2023 Planned End Date changed from 31 Dec 2023 to 31 Dec 2025.
  • 28 Sep 2023 Planned primary completion date changed from 31 Dec 2023 to 31 Dec 2025.
  • 09 Feb 2023 Planned End Date changed from 31 Dec 2022 to 31 Dec 2023.

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