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BLockade of PD-1 Added to Standard Therapy to Target Measurable Residual Disease in Acute Myeloid Leukemia 1 (BLAST MRD AML-1): A Randomized Phase 2 Study of the Anti-PD-1 Antibody Pembrolizumab in Combination With Conventional Intensive Chemotherapy as Frontline Therapy in Patients With Acute Myeloid Leukemia

Trial Profile

BLockade of PD-1 Added to Standard Therapy to Target Measurable Residual Disease in Acute Myeloid Leukemia 1 (BLAST MRD AML-1): A Randomized Phase 2 Study of the Anti-PD-1 Antibody Pembrolizumab in Combination With Conventional Intensive Chemotherapy as Frontline Therapy in Patients With Acute Myeloid Leukemia

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 20 Apr 2025

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At a glance

  • Drugs Pembrolizumab (Primary) ; Cytarabine; Daunorubicin; Haematopoietic stem cell therapy; Idarubicin
  • Indications Acute myeloid leukaemia
  • Focus Therapeutic Use
  • Acronyms BLAST MRD AML-1

Most Recent Events

  • 03 Feb 2025 Planned End Date changed from 31 Jul 2025 to 30 Jan 2026.
  • 26 Nov 2024 Status changed from recruiting to active, no longer recruiting.
  • 15 Aug 2024 Planned End Date changed from 31 Jul 2024 to 31 Jul 2025.

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