Trial Profile

Phase 1/2 Open-label Study of Combination Therapy With the MEK Inhibitor, Cobimetinib, Immune Checkpoint Blockade, Atezolizumab, and the AUTOphagy Inhibitor, Hydroxychloroquine in KRAS-mutated Advanced Malignancies

Status: Discontinued

Phase of Trial: Phase I/II

Latest Information Update: 20 Dec 2024

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At a glance

Drugs Atezolizumab (Primary) ; Cobimetinib (Primary) ; Hydroxychloroquine (Primary)
Indications Adenocarcinoma; Cancer; Colorectal cancer; Pancreatic cancer
Focus Adverse reactions; Therapeutic Use
Acronyms MEKiAUTO

18 Dec 2024 Status changed from active, no longer recruiting to discontinued.
29 Nov 2022 Planned primary completion date changed from 1 Sep 2023 to 1 Jun 2024.
29 Nov 2022 Status changed from recruiting to active, no longer recruiting.

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