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The Effect of GLP-1 Agonist, SGLT2 Inhibitor and Their Combination on Endothelial Function, Arterial Stiffness and Left Ventricular Deformation in Patients With Type 2 Diabetes With High Cardiovascular Risk

Trial Profile

The Effect of GLP-1 Agonist, SGLT2 Inhibitor and Their Combination on Endothelial Function, Arterial Stiffness and Left Ventricular Deformation in Patients With Type 2 Diabetes With High Cardiovascular Risk

Status: Recruiting
Phase of Trial: Phase IV

Latest Information Update: 08 Jun 2025

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At a glance

  • Drugs Empagliflozin (Primary) ; Liraglutide (Primary) ; Insulin; Metformin
  • Indications Cardiovascular disorders; Type 2 diabetes mellitus
  • Focus Pharmacodynamics

Most Recent Events

  • 13 Sep 2024 Results assessing the effect of 12-month treatment with glucagon-like peptide-1 receptor agonists, sodium-glucose cotransporter-2 inhibitors and their combination on cardiac markers and mitochondrial function presented at the 60th Annual Meeting of the European Association for the Study of Diabetes
  • 14 Mar 2024 Planned End Date changed from 30 Jun 2024 to 30 Jun 2027.
  • 14 Mar 2024 Planned primary completion date changed from 31 Dec 2023 to 31 Dec 2026.

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