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Phase 1 Study Investigating the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of the Anti OX40 Agonist Monoclonal Antibody BGB-A445 in Combination With the Anti-PD-1 Monoclonal Antibody Tislelizumab in Patients With Advanced Solid Tumors

Trial Profile

Phase 1 Study Investigating the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of the Anti OX40 Agonist Monoclonal Antibody BGB-A445 in Combination With the Anti-PD-1 Monoclonal Antibody Tislelizumab in Patients With Advanced Solid Tumors

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 27 May 2025

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At a glance

  • Drugs BGB A445 (Primary) ; Tislelizumab (Primary)
  • Indications Head and neck cancer; Non-small cell lung cancer; Solid tumours; Squamous cell cancer
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors BeiGene

Most Recent Events

  • 22 May 2025 According to the BeiGene media release, final analysis from this trial will be presented at the American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago, IL, May 30 -June 3, 2025.
  • 06 Feb 2025 Status changed from active, no longer recruiting to completed.
  • 13 Aug 2024 Planned End Date changed from 16 Sep 2024 to 29 Nov 2024.

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