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Randomized Double Blind Controlled Trial Comparing the Safety and Efficacy of Apremilast Versus Placebo in Severe Forms of Recurrent Aphthous Stomatitis

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Trial Profile

Randomized Double Blind Controlled Trial Comparing the Safety and Efficacy of Apremilast Versus Placebo in Severe Forms of Recurrent Aphthous Stomatitis

Status: Recruiting
Phase of Trial: Phase III

Latest Information Update: 20 Feb 2026

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At a glance

  • Drugs Apremilast (Primary)
  • Indications Aphthous stomatitis
  • Focus Therapeutic Use
  • Acronyms PREMS

Most Recent Events

  • 17 Feb 2026 Planned End Date changed from 1 Jun 2027 to 1 Dec 2026.
  • 17 Feb 2026 Planned primary completion date changed from 1 Jun 2027 to 1 Dec 2026.
  • 17 Feb 2026 Status changed from not yet recruiting to recruiting.

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