Trial Profile

A Phase 1/2 Multiple Ascending-Dose Study in Subjects With Homocystinuria Due to Cystathionine β-Synthase (CBS) Deficiency to Investigate the Safety, Pharmacokinetics, and Pharmacodynamics of ACN00177

Status: Discontinued

Phase of Trial: Phase I/II

Latest Information Update: 24 Jan 2024

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At a glance

27 Nov 2023 According to Spyre Therapeutics media release, Aeglea Biotherapeutics has changed its name to Spyre Therapeutics
25 Jul 2023 Status changed from recruiting to discontinued.
12 Apr 2023 According to an Aeglea Biotherapeutics media release, 13 participants were enrolled in the clinical trial and 11 participants completed dosing. One participant withdrew from the trial due to personal reasons.

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